Dr Scott Cameron

Dr Scott Cameron profile picture

Scientist Ferrier Research Institute

Courses

Teaching in 2019

With a career working in inorganic chemistry, organic chemistry and biochemistry, you could say Dr Scott Cameron is a jack-of-all-chemistry-trades.

After completing his PhD in inorganic chemistry at the University of Otago Scott has worked with the Carbohydrate Chemistry group (then part of Industrial Research Limited) and has completed a post-doc at the Albert Einstein College of Medicine in New York, where he expanded his repertoire to include protein crystallography and branched out to biochemistry and enzymology.

As the Ferrier Research Institutes’ small-molecule crystallographer, Scott says “X-ray crystal structures are becoming an invaluable tool for our organic chemistry team, providing essential stereochemistry information—being able to see the atomic-level 3D structure of a compound or protein is incredible”.

Scott is currently interested in establishing the technique of transition-state analysis within the Ferrier group. This will allow them to investigate the precise nature of the transition state of an enzyme, the key, fleeting moment in an enzymatic reaction before conversion of a substrate to product.

The information gleaned from this technique can then be used as a kind of “blueprint” for the design of chemically stable transition-state analogues, which will hopefully yield some extremely powerful enzyme inhibitors.

“This rational approach to enzyme inhibition combines all of my skills and the concept is really fascinating to me. It’s amazing how potent some of the inhibitors are that have been discovered using this approach”

Publications

View Scott's publications on Google Scholar.

Courses

Teaching in 2019