School of Biological Sciences

Cell and Immunobiology

Dr Anne Camille La Flamme

Modifying the immune climate from a pro- (left) to an anti-inflammatory climate (right) reduces the infiltration of brown-stained macrophages into the spinal cord of a mouse model of MS.

We study immunoregulation - the mechanisms that regulate the immune system - from several complementary perspectives. Our research is investigating how the immune system can be enhanced or modified to prevent serious disease from infectious agents or autoimmunity.

The autoimmune disease multiple sclerosis (MS) is a major research focus. We are investigating how the immune system can be modified to prevent disease as well as trying to find new targets for future MS therapies.

We have a strong connection to the Malaghan Institute for Medical Research on campus, as Dr Anne La Flamme heads their Multiple Sclerosis Research Group.

We are also involved in other aspects of immune regulation including:

  • modulation of macrophage and microglial function
  • effects of unique marine products on immune cell functions
  • anti-microbial immune responses of tuatara with researchers from the Allan Wilson Centre
  • cardio-protective mechanism of remote ischemic preconditioning (temporarily stopping blood flow to a limb to protect the heart during heart surgery) with investigators at Wellington Hospital.

Read more about our MS research and our research into schistosomiasis.


People

Group Leader

Anne Camille La Flamme


Research Assistants

Dr Dahna Fong

Dr Bhagyashree Manivannan


Students

David O’Sullivan

Sarrabeth Stone

Danielle Middleton

Delgertsetseg Chuluundorj

Marie Kharkrang

Jennifer Williams

Lisa Johnston

Madeleine White


Contact

Please contact Anne La Flamme for more information.