Department of Microbiology and Immunology, University of Otago
Targeting bacterial energetics to fight drug-resistant pathogens
The emergence and spread of drug-resistant pathogens and our inability to develop new antimicrobials to combat resistance (phenotypic and genetic) has motivated scientists to consider non-traditional targets for drug development where human homologs clearly exist. Cellular bioenergetics is an area showing promise for the development of new antimicrobials, but the success of this area will only emerge by understanding the role of these energetic processes (e.g. respiration and oxidative phosphorylation) under conditions that prevail in host tissues. In this seminar, I will examine the recent developments in the field suggesting cellular energetics as a target space for the development of new antimicrobials.
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All under-graduate students and interested parties are welcome to join.